Author Zafar, Saima
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2024 | Journal Article
Current Technologies Unraveling the Significance of Post-Translational Modifications (PTMs) as Crucial Players in Neurodegeneration
Zafar, S.; Fatima, S. I.; Schmitz, M. & Zerr, I. (2024)
Biomolecules, 14(1) pp. 118. DOI: https://doi.org/10.3390/biom14010118
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2024 | Journal Article
A systemic analysis of Creutzfeldt Jakob disease cases in Asia
Rasheed, U.; Khan, S.; Khalid, M.; Noor, A. & Zafar, S. (2024)
Prion, 18(1) pp. 11-27. DOI: https://doi.org/10.1080/19336896.2024.2311950
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2023 | Journal Article |
α-Synuclein conformers reveal link to clinical heterogeneity of α-synucleinopathies
Schmitz, M. ; Candelise, N.; Canaslan, S.; Altmeppen, H. C.; Matschke, J.; Glatzel, M. & Younas, N. et al. (2023)
Translational Neurodegeneration, 12(1) art. 12. DOI: https://doi.org/10.1186/s40035-023-00342-4
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2023 | Journal Article
The Role of Tau Proteoforms in Health and Disease
Waheed, Z.; Choudhary, J.; Jatala, F. H.; Fatimah, F.; Noor, A.; Zerr, I. & Zafar, S. (2023)
Molecular Neurobiology,. DOI: https://doi.org/10.1007/s12035-023-03387-8
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2023 | Journal Article
Genetic Variants Associated with the Age of Onset Identified by Whole-Exome Sequencing in Fatal Familial Insomnia
Thüne, K.; Schmitz, M.; Wiedenhöft, J.; Shomroni, O.; Göbel, S.; Bunck, T. & Younas, N. et al. (2023)
Cells, 12(16) pp. 2053. DOI: https://doi.org/10.3390/cells12162053
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2023 | Journal Article |
Differential interactome mapping of aggregation prone/prion-like proteins under stress: novel links to stress granule biology
Younas, N. ; Zafar, S.; Saleem, T.; Fernandez Flores, L. C.; Younas, A.; Schmitz, M. & Zerr, I. (2023)
Cell & Bioscience, 13(1). DOI: https://doi.org/10.1186/s13578-023-01164-7
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2022 | Journal Article |
SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA-Linked Parkinson’s Disease Patients
Zafar, S.; Noor, A.; Younas, N.; Shafiq, M.; Schmitz, M.; Wurster, I. & Brockmann, K. et al. (2022)
International Journal of Molecular Sciences, 23(22) pp. 14166. DOI: https://doi.org/10.3390/ijms232214166
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2021 | Journal Article |
Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease
Noor, A.; Zafar, S.; Shafiq, M.; Younas, N.; Siegert, A.; Mann, F. A. & Kruss, S. et al. (2021)
Molecular Neurobiology, 59(1) pp. 17-34. DOI: https://doi.org/10.1007/s12035-021-02566-9
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2021 | Journal Article |
Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease
Cheng, L.; Quek, C.; Li, X.; Bellingham, S. A.; Ellett, L. J.; Shambrook, M. & Zafar, S. et al. (2021)
Communications Biology, 4(1). DOI: https://doi.org/10.1038/s42003-021-01868-x
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2021 | Journal Article | Research Paper |
Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer’s disease
Shafiq, M.; Zafar, S.; Younas, N.; Noor, A.; Puig, B.; Altmeppen, H. C. & Schmitz, M. et al. (2021)
Molecular Neurodegeneration, 16(1) art. 11. DOI: https://doi.org/10.1186/s13024-021-00422-x
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2021 | Journal Article | Research Paper |
Cellular Prion Protein Mediates α‐Synuclein Uptake, Localization, and Toxicity In Vitro and In Vivo
Thom, T.; Schmitz, M.; Fischer, A.; Correia, A.; Correia, S.; Llorens, F. & Pique, A. et al. (2021)
Movement Disorders, 37(1) art. mds.28774. DOI: https://doi.org/10.1002/mds.28774
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2019 | Book Chapter
Therapies for prion diseases
Zafar, S.; Noor, A.& Zerr, I. (2019)
In: Psychopharmacology of Neurologic Disease pp. 47-58. Elsevier. DOI: https://doi.org/10.1016/B978-0-444-64012-3.00004-6
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2018 | Book Chapter
Cerebrospinal fluid in Creutzfeldt–Jakob disease
Zerr, I.; Zafar, S.; Schmitz, M.& Llorens, F. (2018)
In: Cerebrospinal Fluid in Neurologic Disorders pp. 115-124. Elsevier. DOI: https://doi.org/10.1016/B978-0-12-804279-3.00008-3
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2017 | Journal Article
Strain-Specific Altered Regulatory Response of Rab7a and Tau in Creutzfeldt-Jakob Disease and Alzheimer's Disease
Zafar, S.; Younas, N.; Correia, S. ; Shafiq, M.; Tahir, W.; Schmitz, M. & Ferrer, I. et al. (2017)
Molecular Neurobiology, 54(1) pp. 697-709. DOI: https://doi.org/10.1007/s12035-016-9694-8
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2017 | Journal Article |
Dementia with Lewy Bodies: Molecular Pathology in the Frontal Cortex in Typical and Rapidly Progressive Forms.
Garcia-Esparcia, P.; López-González, I.; Grau-Rivera, O.; García-Garrido, M. F.; Konetti, A.; Llorens, F. & Zafar, S. et al. (2017)
Frontiers in neurology, 8 art. 89. DOI: https://doi.org/10.3389/fneur.2017.00089
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2017 | Journal Article |
Cellular prion protein mediates early apoptotic proteome alternation and phospho-modification in human neuroblastoma cells
Zafar, S.; Behrens, C.; Dihazi, H.; Schmitz, M.; Zerr, I.; Schulz-Schaeffer, W. J. & Ramljak, S. et al. (2017)
Cell Death and Disease, 8 art. e2557. DOI: https://doi.org/10.1038/cddis.2016.384
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2016 | Conference Abstract
Prion protein interactome: Identifying novel targets in rapidly progressive Alzheimer's disease
Shafiq, M.; Zafar, S.; Younas, N.; Schmitz, M.; Ferrer, I. & Zerr, I. (2016)
Prion, 10
Philadelphia: Taylor & Francis Inc.
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2016 | Conference Abstract
Genetic prion diseases
Zerr, I.; Schmitz, M.; Zafar, S. & Llorens, F. (2016)
Prion, 10
Philadelphia: Taylor & Francis Inc.
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2016 | Conference Abstract
Early response of Cofilin1 pathway in Creutzfeldt Jakob disease
Younas, N.; Zafar, S.; Shafiq, M.; Tahir, W.; Schmitz, M.; Ferrer, I. & Andreoletti, O. et al. (2016)
Prion, 10 pp. S102-S103.
Philadelphia: Taylor & Francis Inc.
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2016 | Journal Article |
Regulation of human cerebrospinal fluid malate dehydrogenase 1 in sporadic Creutzfeldt-Jakob disease patients
Schmitz, M.; Llorens, F.; Pracht, A.; Thom, T.; Correia, A. ; Zafar, S. & Ferrer, I. et al. (2016)
Aging, 8(11) pp. 2927-2935. DOI: https://doi.org/10.18632/aging.101101
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